Molecular Formula | C4H14Cl2N2 |
Molar Mass | 161.07 |
Density | 1.2524 (rough estimate) |
Melting Point | 280°C (dec.)(lit.) |
Boling Point | 265.47°C (rough estimate) |
Flash Point | 51.7°C |
Water Solubility | almost transparency |
Solubility | Easily soluble in water, can absorb carbon dioxide |
Vapor Presure | 2.55mmHg at 25°C |
Appearance | White crystalline powder |
Color | White |
Merck | 14,7947 |
BRN | 3906680 |
Storage Condition | Store below +30°C. |
Stability | Stable, but hygroscopic. Substances to be avoided: strong oxidizing agents. Combustible. |
Sensitive | Hygroscopic |
Refractive Index | 1.6300 (estimate) |
MDL | MFCD00012526 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | EJ7280000 |
TSCA | Yes |
HS Code | 29212900 |
Reference Show more | 1. Zhang Chengfeng, Li Shuo, Shi Yu, et al. Effects of seed soaking with putrescine on growth and physiological resistance of cucumber seedlings under Ca(NO3)2 stress [J]. Shandong Agricultural Sciences, 2019, 051(012):67-72. 2. Wang Jie, Wang dujun, Li Fengwei, etc. Optimization of conditions for enrichment of γ-aminobutyric acid and flavonoids from Salicornia seed germination and study on key enzyme activities [J]. Food Research and Development, 2019, v.40;No.372(23):66-73. 3. Ma Yue, Li Yongcai, Hu Peifang, etc. Effects of post-harvest polyamine treatment on control of black spot and storage quality of apricot fruit [J]. Food Science, 2018. 4. Wu Xiaohe, Geng Xiaojie, Zhang Jianxu, etc. Study on microbiology and physicochemical properties of Huanghua shrimp paste [J]. Food Research and Development, 2019, v.40;No.361(12):83-89. 5. Hou Ying, Qi Xuehe, Ren Hui, Hong Shiyu, Chi zonyu, Wang Hongfei, Xu Feng. Effect of fresh-cut treatment on enrichment of γ-aminobutyric acid in kiwifruit [J]. Science and Technology of food industry, 2020,41(20):58-63 84. 6. Cao Shaoqian, Madani, Cai Jinxiu, Ma Jiawen, Wang Zhengdong, Qi Xiangyang. Effect of degreasing and deodorization on the quality of bighead carp protein powder [J]. Food Science and Technology, 2020,45(12):128-134. 7. Li Silk, Li Yingyan, Yin Xiaoqing, Liu Liang, Cao Shaoqian, Madani, Qi Xiangyang. Processing Technology and Quality Analysis of fresh fish juice prepared by fish meal processing and squeezing liquid [J]. Chinese Journal of Food Science, 2020,20(10):160-168. 8. Sarina, Tuerhong, mimetti, aziguli, Yikui, Ibani, aidijiang, aiifu, bub, Zhang. Determination of eight biogenic amines in soy sauce by liquid chromatography-tandem mass spectrometry (LC-MS)[J]. Chinese condiment, 2020,45(11):151-156. 9. Liu, B., jiang, X., cai, L. et al. Putrescine mitigates intestinal atrophy through suppressing inflammatory response in weanling piglets. J Animal Sci Biotechnol 10, 69 (2019). https://doi.org/10.1186/s40104-019-0379-9 10. [IF=4.215] Zhu Xujun et al."Physiological and iTRAQ-based proteomic analyses reveal the function of exogenous γ-aminobutyric acid (GABA) in improving tea plant (Camellia sinensis L.) tolerance at cold temperature."Bmc Plant Biol. 2019 Dec;19(1):1-20 11. [IF=7.514] Yongcai Li et al."Exogenous polyamines enhance resistance to Alternaria alternata by modulating redox homeostasis in apricot fruit."Food Chem. 2019 Dec;301:125303 12. [IF=7.514] Tian-tian Zhou et al."Novel carrier-mediated membrane-assisted three-phase liquid-liquid extraction coupled with liquid chromatography-mass spectrometry for the determination of eight biogenic amines in foods."Food Chem. 2022 Sep;387:132857 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Application | 1,4-butyldiamine dihydrochloride is an organic intermediate, which can be prepared from 1, 4-butyldiamine and hydrogen chloride into salt. There are reports that it can be used to prepare a culture medium for stem cell culture. |
preparation | 880 kg1, 4-butylenediamine and 4990kg toluene are mixed into a salt-forming reactor and stirred evenly. Then, the temperature in the reactor is controlled at 15 ℃, the reaction pressure is 0.12MPa, and the hydrogen chloride gas is blown into the reactor at a speed of 370 Nm3/h through the hydrogen chloride gas blowing tube. After 3 hours, the hydrogen chloride is stopped to obtain diamine hydrochloride solution. The obtained hydrochloride is filtered and dried in a three-in-one machine to obtain 1, 4-butylene diamine dihydrochloride solid. |
biological activity | 1,4-Diaminobutane dihydrochloride is an endogenous metabolite, which can be used as an indicator of higher plant barley and rape pollution caused by Cr (III) or Cr (VI) stress. |
target | Human Endogenous Metabolite |
use | for biochemical research. Organic synthesis. |